· You might want to mv the executables into the bin/ folder on your accounts rather than the paml main folder. And finally, if your current folder is not on your search path, you will have to add./ in front fo the executable file name; that is, use./codeml instead of codeml to run codeml. MAC OS X. You should open a command terminal (Applications-Utilities-Terminal) and then compile and run the . · CodeML is a program from the package PAML, based on Maximum Likelihood, and developed in the lab of Ziheng Yang, University College London. It estimates various parameters (Ts/Tv, dN/dS, branch length) on the codon (nucleotide) alignment, based on a predefined topology (phylogenetic tree). Different categories of codon models exist in CodeML. 2 PAML MANUAL baseml and codeml. The program baseml is for maximum likelihood analysis of nucleotide sequences. The program codeml is formed by merging two old programs: codonml, which implements the codon substitution model of Goldman and Yang () for protein-coding DNA sequences, and aaml, which implements models for amino acid sequences.
When you are ready to run CODEML, delete the ex1_ prefix from the control file and the seq file (e.g., the control file must be called www.doorway.ru). Create a directory where you want your results to go, and place all your files within it. Now open a terminal, move to the directory that contains your files, and run CODEML. 2 PAML MANUAL baseml and codeml. The program baseml is for maximum likelihood analysis of nucleotide sequences. The program codeml is formed by merging two old programs: codonml, which implements the codon substitution model of Goldman and Yang () for protein-coding DNA sequences, and aaml, which implements models for amino acid sequences. www.doorway.ru www.doorway.ru www.doorway.ru or www.doorway.ru www.doorway.ru Introduction to Model and realistic usage. Basic Model.
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